Arthrosamid® Knee Injection

Long-lasting relief for knee osteoarthritis.

Arthrosamid® is a new, long-acting injectable hydrogel treatment for knee osteoarthritis. It works by forming a soft, cushioning layer inside the joint to reduce friction and ease pain — often after just one injection.

What is Arthrosamid used for?

Arthrosamid is used to treat pain from knee osteoarthritis (OA). It may be suitable for people with mild to moderate OA who still have symptoms despite lifestyle measures, physiotherapy, or other injections such as corticosteroids or hyaluronic acid.

How is the treatment given?

A trained clinician injects 6 ml of Arthrosamid directly into the knee joint under ultrasound guidance. The procedure takes around 15–20 minutes, with minimal discomfort, and patients can usually walk out immediately afterwards.

What does the evidence show?

Clinical studies show that a single Arthrosamid injection can provide meaningful and lasting pain relief, with benefits maintained for several years.

Study Duration Key Findings
1 year Pain scores reduced by about 25%; 62% of patients experienced meaningful pain relief.
3 years Ongoing reduction in pain and stiffness, improved function, and good tolerability.
4–5 years Sustained benefit and consistent safety profile.
10 years (safety) Very few reported adverse effects; no unusual reactions during later knee surgery.

Is Arthrosamid safe?

Arthrosamid has been used in clinical studies for more than a decade and has shown a very good safety record. Side effects are generally mild and short-lived, such as temporary swelling or mild discomfort in the injected knee.

It contains no animal proteins, and allergic reactions are rare.

What to expect after treatment

Most people can resume normal light activity immediately. Avoid strenuous exercise for a few days. Mild swelling or aching may occur for 24–48 hours. Pain relief often begins within a few weeks and may continue to improve over several months as the hydrogel integrates into the joint.

Summary
  • Single injection treatment for knee osteoarthritis
  • Provides cushioning and lubrication inside the joint
  • Proven long-term benefit — up to 5 years
  • Safe, minimally invasive, and well-tolerated

Book a consultation

This information is provided for general educational purposes and should not replace individual medical advice. Please speak with a qualified clinician before deciding on treatment.

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Musculoskeletal medicine
Gardasil vaccinations for HPV related Cervical and anal cancers
Excess sweating ‘Hyperhidrosis’ 
Male Hormone Therapy
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Genetic testing
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Hair Loss: Dutasteride Mesotherapy
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All Services
COVID-19
Sexual Health
Telephone and Video Consultations
Private Blood Testing
Travel & Vaccinations
Wellperson health screening
Allergy Testing
Musculoskeletal medicine
Gardasil vaccinations for HPV related Cervical and anal cancers
Excess sweating ‘Hyperhidrosis’ 
Male Hormone Therapy
Weight loss services
Genetic testing
Cancer and Heart screening
Hair Loss: Dutasteride Mesotherapy
Athrosamid
Philosophy
NAD+ IV infusions
Pricing
Our team
Media
Blog
Contact
0207 139 1833
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