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Assessing HIV Risk

Whilst no risk estimate can ever be exact, decades of research have allowed us to estimate the relative risk associated with different exposures.

Understanding HIV Transmission Risk

One of the most common questions we are asked is:

“What are my chances of catching HIV from this exposure?”

Whilst no risk estimate can ever be exact, decades of research have allowed us to estimate the relative risk associated with different exposures.

The figures below assume exposure to a partner with untreated HIV and a detectable viral load.

They do not apply if the source partner is known to have a sustained undetectable viral load, as U=U (Undetectable = Untransmittable) means there is effectively no risk of sexual HIV transmission.

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Anal Intercourse

Anal intercourse carries the highest sexual risk of HIV transmission because the lining of the rectum is particularly susceptible to microscopic injury.

Estimated risks per exposure:

  • Receptive anal intercourse: approximately 1 in 90
  • Receptive anal intercourse with ejaculation: approximately 1 in 65
  • Receptive anal intercourse without ejaculation: approximately 1 in 170
  • Insertive anal intercourse: approximately 1 in 170
  • Insertive anal intercourse (uncircumcised): approximately 1 in 161
  • Insertive anal intercourse (circumcised): approximately 1 in 909

These figures are averages and individual risk varies considerably depending on viral load, condom use, presence of other sexually transmitted infections and use of PrEP.

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Vaginal Intercourse

The risk of HIV transmission during vaginal intercourse is generally lower than for anal intercourse but remains significant when HIV is present and untreated.

Estimated risks per exposure:

  • Receptive vaginal intercourse: approximately 1 in 1,000
  • Insertive vaginal intercourse: approximately 1 in 1,219

Again, factors such as viral load, condom use, PrEP use and co-existing STIs can significantly influence risk.

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Oral Sex

Oral sex is one of the most misunderstood aspects of HIV medicine.

Many patients are surprised to learn that HIV transmission through oral sex appears to be extremely uncommon.

Estimated risks:

  • Receptive oral sex (giving fellatio): less than 1 in 10,000
  • Insertive oral sex (receiving fellatio): less than 1 in 10,000
  • Semen splash to the eye: less than 1 in 10,000

Whilst these risks are extremely low, individual circumstances should always be considered.

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Other Routes Of Transmission

Estimated risks include:

  • Sharing injecting equipment: approximately 1 in 149
  • Needlestick injury: approximately 1 in 333
  • Human bite: less than 1 in 10,000

Modern blood products in the UK undergo rigorous screening and transfusion-related HIV transmission is now exceptionally rare.

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Why These Numbers Need Context

One of the biggest mistakes people make is focusing solely on the type of exposure whilst ignoring the source.

The actual risk depends upon:

  • Whether the source partner has HIV
  • Whether they are receiving treatment
  • Their viral load
  • Whether PrEP was being taken
  • Whether a condom was used
  • Presence of other sexually transmitted infections

For example, receptive anal intercourse with a partner who has untreated HIV carries a very different risk from receptive anal intercourse with a partner who has a sustained undetectable viral load.

This is why personalised risk assessment remains far more useful than relying solely on published statistics.

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Meet our team

Dr Daniel Wright
MD MRCGP MA (Hons) BA (Hons)
Dr. Susan Jain
MD MRCGP MA (Hons) BA (Hons)
Nathan Hunt
Practice Manager

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101 Harley Street, London, W1G 6AH

The Wright Practice

101 Harley Street, London, W1G 6AH, United Kingdom

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