NAD+ (Nicotinamide Adenine Dinucleotide) is a molecule found in every cell of the body, responsible for energy transfer, cellular repair, and hundreds of metabolic processes.
The male menopause, also known as testosterone deficiency, androgen deficiency, or late-onset hypogonadism, refers to the gradual decline in testosterone that most men experience from their mid-thirties onwards. Unlike the female menopause, the change is gradual rather than sudden, which means symptoms often creep up slowly and go unrecognised for years.
The condition affects a significant proportion of men over 40 and a growing number of younger men, and it is frequently dismissed or misattributed. You can read more in our blog post on the male menopause.
Symptoms of low testosterone can affect almost every aspect of daily life. Common ones include: persistent fatigue that is not explained by sleep or workload; low libido and reduced interest in sex; erectile dysfunction or reduced quality of erections; low mood, irritability, or a flat feeling that does not lift; difficulty concentrating; reduced muscle mass and increased body fat, particularly around the abdomen; loss of body hair; and sleep difficulties.
These symptoms overlap with many other conditions, which is why proper blood testing and a thorough consultation are essential before reaching any conclusion.
A blood test measures total testosterone, free testosterone, SHBG (sex hormone binding globulin), and other relevant markers. Because testosterone levels fluctuate through the day and are affected by sleep, stress, and illness, Dr Dan interprets results in the context of your full clinical picture rather than relying on a single number.
Normal ranges are broad, and some men feel symptoms at levels that would appear within the normal reference range. Dr Dan takes the patient’s experience seriously alongside the numbers. You can read more about SHBG and its role in testosterone availability in our blog post on SHBG and active testosterone.
Testogel (topical gel) Applied daily to the shoulders, arms, or abdomen. Easy to use, avoids injections, and has a good long-term cardiovascular safety profile. The main considerations are daily application, variability in absorption between individuals, and the small risk of transfer to another person through skin contact.
Nebido (testosterone undecanoate) A long-acting injection given every three months after an initial loading period. It requires only four injections per year, but levels fluctuate over the three-month cycle and dose adjustment is less flexible.
Sustanon A blend of four testosterone esters given every one to three weeks, or used in smaller microdoses once or twice a week. It offers more flexibility and is well suited to microdosing protocols. Both Nebido and Sustanon are licensed in the UK.
The right choice depends on your lifestyle, preference, and clinical profile. Dr Dan will discuss the options and make a recommendation based on your individual situation.
Common minor side effects include acne, fluid retention, and increased urination. More significant risks include effects on fertility, increased red blood cell count (which can increase clotting risk), changes in cholesterol, and worsening of sleep apnoea if already present. Dr Dan monitors for all of these throughout treatment.
Before starting treatment, Dr Dan will arrange a comprehensive blood test including testosterone levels, PSA (prostate-specific antigen), full blood count, and other relevant markers. During treatment, free testosterone levels, PSA, and haematocrit (red blood cell count) are monitored regularly.
An initial consultation is £185 for registered patients or £215 for new patients. Testosterone medication costs vary depending on the type prescribed. Full pricing is on the pricing page.
Dr Dan takes a careful, evidence-based approach to male hormone therapy. The goal is not simply to bring testosterone levels into a normal range on paper, but to help each patient feel well and function at their best. That means thorough assessment, honest conversations about risks and benefits, and close monitoring throughout. Sleep, stress, diet, and exercise are also addressed alongside any medication.
Wow! Dr. Dan was extremely knowledgeable and attentive to my health and well being. I’m so glad to have found him!
I have been going to Dr Wright for a number of years now. He is highly knowledgeable, compassionate, open minded and efficient, I couldn’t recommend him highly enough
I have been a patient of Doctor Dan for some time and continue to consult with him despite having left the UK. Dan has the enthusiasm and energy of a young man, whilst taking the holistic “physician” approach of an old school family doctor, equipped with the most modern insights and technology.
Dr Jain was great. Expert knowledge with practical advice
Oral supplements must pass through the digestive system, where absorption is variable and often limited. An IV infusion delivers NAD+ directly into the bloodstream, ensuring full absorption and a more immediate effect on cellular NAD+ levels.
NAD+ infusions typically take two to four hours depending on the dose, as the infusion needs to be administered slowly. Standard nutrient infusions are faster, usually 30 to 60 minutes.
Some patients experience mild warmth, flushing, or a sensation of pressure in the chest during the infusion. These sensations are temporary and settle quickly when the drip rate is slowed.
Some patients notice improved energy and mental clarity within a day or two of their first infusion. The effect tends to build with subsequent infusions in the course.
Yes. NAD+ therapy fits naturally alongside health screening, genetic testing, and hormone optimisation as part of a proactive longevity strategy.
Yes. We offer a range of nutrient infusions without NAD+ at £395 each, including Energiser, Immune Boost, Hair Nourishment, Athletes Sport, and the Comprehensive formula.
No. NAD+ therapy is currently available only through private clinics.
NAD+ infusions are not recommended for patients who are pregnant or breastfeeding, or who have certain metabolic or kidney conditions. Dr Dan will review your medical history and blood results before treatment to confirm suitability.
Book online | Call: +44 (0)207 139 1833 | Email: info@thewrightpractice.com
101 Harley Street, London, W1G 6AH
Rated ★ ★ ★ ★ ★ from 192 Reviews
