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Syphilis Testing and Treatment in London

Private syphilis testing at 101 Harley Street. Blood tests, accurate diagnosis across all stages and expert treatment. Confidential, same-day appointments available.

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum.

Although often perceived as a disease of the past, syphilis has become increasingly common throughout the UK and many other parts of the world over the last decade. It remains one of the most important sexually transmitted infections because of its ability to mimic a wide range of other conditions and because untreated infection can occasionally lead to serious long-term complications.

How Is Syphilis Transmitted?

Syphilis is most commonly transmitted through direct contact with a syphilitic sore, known as a chancre.

Transmission may occur during:

  • Vaginal sex
  • Anal sex
  • Oral sex
  • Genital-to-genital contact

The infection can also be transmitted from mother to baby during pregnancy, known as congenital syphilis.

Importantly, syphilis is not spread through casual contact such as sharing toilets, cutlery, swimming pools or everyday social interaction.

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What Are The Symptoms?

One of the challenges with syphilis is that symptoms vary considerably depending on the stage of infection.

Primary Syphilis

The earliest stage usually presents with a painless ulcer known as a chancre.

This often appears at the site of infection and may occur on:

  • Penis
  • Vulva
  • Cervix
  • Rectum
  • Mouth
  • Throat

Because the lesion is typically painless and often hidden from view, many patients never realise it was present.

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Secondary Syphilis

Several weeks later, untreated infection may progress to secondary syphilis.

Symptoms may include:

  • Rash
  • Enlarged lymph nodes
  • Fever
  • Sore throat
  • Fatigue
  • Headaches
  • Patchy hair loss

The rash classically affects the palms of the hands and soles of the feet, although this is not always the case.

Again, symptoms often resolve spontaneously even without treatment, leading some individuals to believe the problem has disappeared.

Latent and Late Syphilis

Latent Syphilis

Following the secondary stage, the infection may enter a latent phase where no symptoms are present.

Individuals may remain completely well for many years whilst still carrying the infection.

Late Syphilis

If left untreated, syphilis can occasionally affect:

  • Brain
  • Nervous system
  • Heart
  • Blood vessels
  • Eyes

Fortunately, modern screening and treatment mean these complications are now relatively uncommon in developed healthcare systems.

How Is Syphilis Diagnosed?

Most syphilis testing is performed using blood tests.

Modern laboratory testing can detect antibodies produced by the immune system in response to infection.

Depending on the timing of exposure and clinical circumstances, several different blood tests may be used to confirm the diagnosis and determine whether infection is active.

Where a suspicious ulcer is present, it may occasionally be possible to identify the organism directly using molecular testing.

Understanding Window Periods

As with all sexually transmitted infections, there is a period following exposure during which testing may be negative despite infection being present.

The timing of testing is therefore important.

For patients attending shortly after an exposure, repeat testing may occasionally be recommended depending on the circumstances.

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How Is Syphilis Treated?

The good news is that syphilis remains highly treatable.

Treatment most commonly involves antibiotics, often administered by injection.

The exact treatment regimen depends on:

  • Stage of infection
  • Previous treatment history
  • Clinical findings
  • Blood test results

Follow-up blood tests are usually performed after treatment to confirm an appropriate response.

Why Is Early Diagnosis Important?

Most people diagnosed with syphilis today make a complete recovery.

However, early diagnosis allows treatment before complications develop and reduces the risk of onward transmission to sexual partners.

For this reason, syphilis remains a core component of modern sexual health screening programmes.

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Frequently Asked Questions

Can syphilis be completely cured?

Yes. When identified at any stage, syphilis is highly treatable with antibiotics. The earlier treatment begins, the lower the risk of any complications. Follow-up blood tests are used to confirm that treatment has been effective.

How soon after exposure can syphilis be detected on a blood test?

There is a window period following exposure during which antibodies may not yet be detectable. This period varies, and Dr Dan Wright will advise on the most appropriate timing for testing based on the circumstances of your exposure.

Is syphilis testing confidential?

All consultations and test results at The Wright Practice are strictly confidential. Results are not shared with your GP or any third party without your explicit consent, except in circumstances required by law.

Can I have syphilis without any symptoms?

Yes. It is entirely possible to carry syphilis through the latent phase with no symptoms at all. This is one of the reasons regular sexual health screening is recommended for sexually active individuals, particularly those with new or multiple partners.

What happens if syphilis is left untreated?

Untreated syphilis can progress through primary, secondary and latent stages before potentially causing serious complications affecting the heart, nervous system and other organs. These complications develop over many years and are entirely preventable with prompt diagnosis and treatment.

Meet our team

Dr Daniel Wright
MD MRCGP MA (Hons) BA (Hons)
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Dr. Susan Jain
MD MRCGP MA (Hons) BA (Hons)
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Nathan Hunt
Practice Manager
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What our patients say on Google

Wow! Dr. Dan was extremely knowledgeable and attentive to my health and well being. I’m so glad to have found him!

John Rutherford
John Rutherford

I have been going to Dr Wright for a number of years now. He is highly knowledgeable, compassionate, open minded and efficient, I couldn’t recommend him highly enough

Peter Jones
Peter Jones

I have been a patient of Doctor Dan for some time and continue to consult with him despite having left the UK. Dan has the enthusiasm and energy of a young man, whilst taking the holistic “physician” approach of an old school family doctor, equipped with the most modern insights and technology.

Steve Smith
Steve Smith

Dr Jain was great. Expert knowledge with practical advice

George Mosley
George Mosley

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Schedule a consultation | Call: +44 (0)207 139 1833 | Email: info@thewrightpractice.com

101 Harley Street, London, W1G 6AH

The Wright Practice

101 Harley Street, London, W1G 6AH, United Kingdom

Rated ★ ★ ★ ★ ★ from 197 Reviews

Opening hours
Monday
9.00 - 17.00
Tuesday
9.00 - 17.00
Wednesday
9.00 - 17.00
Thursday
9.00 - 17.00
Friday
9.00 - 17.00
Saturday
9.00 - 17.00
Sunday
Closed
The Wright Practice
101 Harley Street, London, W1G 6AH, United Kingdom
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